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How do cells control that the proteins they produce possess the correct structure? How is it ensured that defective proteins are recognized and degraded instead of having potentially harmful effects on the organism? Which molecules and mechanisms underlie this molecular quality control? Professor M. Feige (b. 1979) addresses these questions with a particular focus on both secretory and membrane proteins. These protein classes play an important role in the interaction of cells with their environment, e.g. in the human immune system. In Professor Feige’s lab for Cellular Protein Biochemistry a particular emphasis is laid on proteins of direct medical relevance so that insights into the principles of cellular quality control might ultimately be translated into new biomedical and biotechnological applications.
How do cells control that the proteins they produce possess the correct structure? How is it ensured that defective proteins are recognized and degraded instead of having potentially harmful effects on the organism? Which molecules and mechanisms underlie this molecular quality control? Professor M. Feige (b. 1979) addresses these questions with a particular focus on both secretory and membrane proteins. These protein classes play an important role in the interaction of cells with their environment, e.g. in the human immune system. In Professor Feige’s lab for Cellular Protein Biochemistry a particular emphasis is laid on proteins of direct medical relevance so that insights into the principles of cellular quality control might ultimately be translated into new biomedical and biotechnological applications.
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论文共 67 篇作者统计合作学者相似作者
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Dorothea Höpfner, Adam Cichy,Vivian Pogenberg,Christoph Krisp,Soraya Mezouar, Nina C Bach, Jan Grotheer,Sandra Madariaga Zarza,Eric Martinez, Matteo Bonazzi,Matthias J Feige,Stephan A Sieber,
Karen Hildenbrand,Sina Bohnacker, Priyanka Rajeev Menon, Anna Kerle, Ulrich F Prodjinotho,Franziska Hartung, Patrick C Strasser,Dragana A M Catici,Florian Rührnößl,Martin Haslbeck, Kathrin Schumann,Stephanie I Müller,
Science Advancesno. 43 (2023): eadg6874-eadg6874
Isabel Aschenbrenner,Till Siebenmorgen,Abraham Lopez,Marina Parr, Philipp Ruckgaber, Anna Kerle,Florian Rührnößl,Dragana Catici,Martin Haslbeck,Dmitrij Frishman,Michael Sattler,Martin Zacharias,
Journal of molecular biologyno. 23 (2023): 168300-168300
Sina Bohnacker, Fiona Henkel,Franziska Hartung, Arie Geerlof,André Mourão,Antonie Lechner,Francesca Alessandrini, Agnieszka M. Kabat, Edward Pearce,Yannick Schreiber,Dominique Thomas, David Vöhringer,
Allergy and immunology (2022)
Yonatan G Mideksa,Isabel Aschenbrenner,Anja Fux, Dinah Kaylani, Caroline A M Weiß,Tuan-Anh Nguyen,Nina C Bach,Kathrin Lang,Stephan A Sieber,Matthias J Feige
The Journal of biological chemistryno. 12 (2022): 102677-102677
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