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Dr. Kaul and his laboratory study cellular and molecular mechanisms of host-virus interactions linked to neurodegenerative diseases, such as HIV-associated neurocognitive disorders and dementia, and NeuroCOVID. The research addresses mechanisms of chronic HIV infection and persistence, neuronal injury and death as well as neuroprotection, the role of interferon-β (IFNβ), cytokines, chemokines, acute phase proteins, such as lipocalin-2, lipid mediators, such as cysteinyl leukotrienes, and their receptors, the contribution of macrophages, microglia, and astrocytes, and their cellular signal transduction. Another focus is the influence of drug abuse on neural plasticity and host-pathogen interactions, in particular HIV-1 infection. A more recently evolving research area is mechanism of virus assembly.
Dr. Kaul and his laboratory study cellular and molecular mechanisms of host-virus interactions linked to neurodegenerative diseases, such as HIV-associated neurocognitive disorders and dementia, and NeuroCOVID. The research addresses mechanisms of chronic HIV infection and persistence, neuronal injury and death as well as neuroprotection, the role of interferon-β (IFNβ), cytokines, chemokines, acute phase proteins, such as lipocalin-2, lipid mediators, such as cysteinyl leukotrienes, and their receptors, the contribution of macrophages, microglia, and astrocytes, and their cellular signal transduction. Another focus is the influence of drug abuse on neural plasticity and host-pathogen interactions, in particular HIV-1 infection. A more recently evolving research area is mechanism of virus assembly.
研究兴趣
论文共 106 篇作者统计合作学者相似作者
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BRAIN BEHAVIOR AND IMMUNITY (2024): 149-166
Brain, behavior, and immunity (2024): 1-21
Tyler Jang,Marcus Kaul
Research square (2024)
Indira Harahap-Carrillo,Ricky Maung,Daniel Ojeda-Juárez,Paloma Sanchez-Pavon,Ana Sanchez,Amanda Roberts,Marcus Kaul, T Tmarc Group
IBRO Neuroscience Reports (2023): S423
Scientific Reportsno. 1 (2023): 1-12
Kristina V Bergersen,Kathy Pham,Jiang Li, Michael T Ulrich, Patrick Merrill,Yuxin He, Sumaya Alaama,Xinru Qiu, Indira S Harahap-Carrillo,Keita Ichii,Shyleen Frost,Marcus Kaul,
JOURNAL OF NEUROVIROLOGY (2023): S36-S37
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NATURE REVIEWS NEUROLOGYno. 11 (2023): 668-687
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