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In 2013, Esvelt was the first to identify the potential for CRISPR “gene drive” systems to alter wild populations of organisms. Recognizing the implications of an advance that could enable individual scientists to alter the shared environment, he and his colleagues chose to break with scientific tradition by revealing their findings and calling for open discussion and safeguards before building the first CRISPR-based gene drive system and demonstrating reversibility in the laboratory.
An outspoken advocate of sharing research plans to accelerate discovery and improve safety, Esvelt's MIT lab seeks to accelerate beneficial advances while safeguarding biotechnology against mistrust and misuse. Projects include building catalytic platforms for directed evolution, pioneering new ways of developing ecotechnologies with the guidance of local communities, developing early-warning systems to reliably detect any catastrophic biological threat, applying cryptographic methods to enable secure and universal DNA synthesis screening, and advising policymakers on how best to mitigate global catastrophic biorisks.
An outspoken advocate of sharing research plans to accelerate discovery and improve safety, Esvelt's MIT lab seeks to accelerate beneficial advances while safeguarding biotechnology against mistrust and misuse. Projects include building catalytic platforms for directed evolution, pioneering new ways of developing ecotechnologies with the guidance of local communities, developing early-warning systems to reliably detect any catastrophic biological threat, applying cryptographic methods to enable secure and universal DNA synthesis screening, and advising policymakers on how best to mitigate global catastrophic biorisks.
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论文共 95 篇作者统计合作学者相似作者
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Nature Communicationsno. 1 (2024): 1-13
biorxiv(2024)
Andrea L. Smidler, Eryney Marrogi, Jamie Kauffman,Douglas G. Paton, Kathleen A. Westervelt,George M. Church,Kevin M. Esvelt,W. Robert Shaw,Flaminia Catteruccia
Noam Kolt,Markus Anderljung, Joslyn Barnhart, Asher Brass,Kevin Esvelt,Gillian K. Hadfield,Lennart Heim, Mikel Rodriguez, Jonas B. Sandbrink, Thomas Woodside
arxiv(2024)
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Carsten Baum, Jens Berlips, Walther Chen,Hongrui Cui, Ivan Damgard, Jiangbin Dong,Kevin M. Esvelt, Mingyu Gao,Dana Gretton, Leonard Foner, Martin Kysel,Kaiyi Zhang,
arxiv(2024)
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MOLECULAR ECOLOGY RESOURCESno. 2 (2024): e13901-e13901
bioRxiv : the preprint server for biology (2024)
NATURE COMMUNICATIONSno. 1 (2024)
Dana Gretton,Brian Wang, Rey Edison, Leonard Foner, Jens Berlips, Theia Vogel, Martin Kysel, Walther Chen, Francesca Sage-Ling, Lynn Van Hauwe, Stephen Wooster, Benjamin Weinstein-Raun,
biorxiv(2024)
bioRxiv : the preprint server for biologyno. 4 (2023): 100111-100111
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