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Our long-term research goal is the development of new approaches to the treatment of epilepsy based on a clearer understanding of the necessary steps in seizure initiation and propagation.
The two major themes in the lab are neuronal ion transport and the spread of activity in neural networks. Neuronal ion transport underlies signaling at all fast synapses. The importance of neuronal ion transport was underscored by our recent discovery that reversed ion transport in the immature brain was blocking the effects of the anticonvulsants most commonly used to treat neonatal seizures, and that a safe and well-characterized diuretic could ameliorate this condition.
The two major themes in the lab are neuronal ion transport and the spread of activity in neural networks. Neuronal ion transport underlies signaling at all fast synapses. The importance of neuronal ion transport was underscored by our recent discovery that reversed ion transport in the immature brain was blocking the effects of the anticonvulsants most commonly used to treat neonatal seizures, and that a safe and well-characterized diuretic could ameliorate this condition.
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论文共 258 篇作者统计合作学者相似作者
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Epilepsia (2024)
Frances Rodriguez Lara, Praneel Sunkavalli, Michael Mikaelian, Bryan Golemb,David Y Chung,Ann-Christine Duhaime,Kevin Staley,Beth Costine-Bartell
Epilepsia (2024)
JOURNAL OF CLINICAL INVESTIGATIONno. 5 (2024)
Trevor Balena,Kyle Lillis,Negah Rahmati,Fatemeh Bahari,Volodymyr Dzhala, Eugene Berdichevsky,Kevin Staley
biorxiv(2023)
Trevor Balena,Kyle Lillis,Negah Rahmati,Fatemeh Bahari,Volodymyr Dzhala, Eugene Berdichevsky,Kevin Staley
JOURNAL OF NEUROSCIENCEno. 34 (2023): 6084-6107
biorxiv(2023)
Frances Rodriguez Lara, Praneel Sunkavalli, Michael Mikaelian, Bryan Golemb,Kevin Staley,Beth Costine-Bartell
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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