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个人简介
Weissman and his lab are investigating protein folding and probe the mysteries behind the organizational principles of biological systems through a variety of molecular and technological methods. While technologies like RNA-seq have made it much easier to monitor which genes are being expressed in a cell at any given time, these approaches use messenger RNA as a proxy for proteins. But generally it is proteins, and not RNAs, that mediate a gene’s cellular functions. That means RNA sequencing is an imperfect indicator for what is actually going on in a cell. To address this issue, Weissman developed a method called ribosome profiling, which measures the ribosomes active in a cell -- and the mRNA, soon to become proteins, inside them.
研究兴趣
论文共 446 篇作者统计合作学者相似作者
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Chen Weng,Fulong Yu,Dian Yang,Michael Poeschla,L. Alexander Liggett,Matthew G. Jones,Xiaojie Qiu,Lara Wahlster,Alexis Caulier, Jeffrey A. Hussmann,Alexandra Schnell, Kathryn E. Yost,
Ezgi Hacisuleyman,Caryn R Hale, Natalie Noble, Ji-Dung Luo,John J Fak, Misa Saito,Jin Chen,Jonathan S Weissman,Robert B Darnell
Gayathri Muthukumar,Taylor A. Stevens,Alison J. Inglis, Theodore K. Esantsi,Reuben A. Saunders, Fabian Schulte,Rebecca M. Voorhees,Alina Guna,Jonathan S. Weissman
bioRxiv : the preprint server for biologyno. 6 (2024): 1101-1119.e9
Arnav Mehta,Lynn Bi, Deepika Yeramosu, Michael Bogaev, Martin Jankowiak, Abigail Collins, Aziz Al'Khafaji, Milan Parikh, Mehrtash Babadi, Kyle Evans,Alex Bloemendal, Russell Kunnes,
Cancer Researchno. 7_Supplement (2024)
Brian T Do,Peggy P Hsu, Sidney Y Vermeulen, Zhishan Wang,Taghreed Hirz,Keene L Abbott,Najihah Aziz,Joseph M Replogle, Stefan Bjelosevic, Jonathan Paolino, Samantha Nelson, Samuel Block,
biorxiv(2024)
Asmin Tulpule,Shruti Menon,Marcus Breese, Yone Lin,Hannah Allegakoen, Shruthi Perati,Ann Heslin,Max Horlbeck,Jonathan Weissman,Alejandro Sweet-Cordero,Trever Bivona
bioRxiv : the preprint server for biology (2023)
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Cellno. 14 (2023): 2977-2994.e23
Iain C. Clark,Kristina M. Fontanez,Robert H. Meltzer,Yi Xue,Corey Hayford,Aaron May-Zhang, Chris D'Amato,Ahmad Osman,Jesse Q. Zhang,Pabodha Hettige, Jacob S. A. Ishibashi,Cyrille L. Delley,
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