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There is an increasing awareness of the role of chromatin structure (epigenetics) in the regulation of gene expression and in the genesis or suppression of cancer. Dr. Davie’s research program investigates the role of the enzymes that remodel chromatin structure and function. A component of this research is to understand the mechanisms by which a cell transmits signals from its surface to its nuclear interior to effect changes in gene expression. Signal transduction events impact on histone modifications, which in turn remodel chromatin structure and enable gene expression.
There is an increasing awareness of the role of chromatin structure (epigenetics) in the regulation of gene expression and in the genesis or suppression of cancer. Dr. Davie’s research program investigates the role of the enzymes that remodel chromatin structure and function. A component of this research is to understand the mechanisms by which a cell transmits signals from its surface to its nuclear interior to effect changes in gene expression. Signal transduction events impact on histone modifications, which in turn remodel chromatin structure and enable gene expression.
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Jeffery Venner, Jhannelle Francis, Jillian Rumore,Michael Sargent,James Davie,Meaghan Jones,Charles N. Bernstein
Gastroenterologyno. 5 (2024): S-1115
Sadhana R. N. Sudhakar,Shahper N. Khan, Ariel Clark, Thordur Hendrickson-Rebizant, Shrinal Patel,Ted M. Lakowski,James R. Davie
BIOCHEMISTRY AND CELL BIOLOGYno. 2 (2024): 106-126
Biochemistry and cell biology = Biochimie et biologie cellulaireno. 3 (2023): 204-219
Biochemistry and cell biology = Biochimie et biologie cellulaireno. 2 (2023): 145-158
GENOMEno. 8 (2023): 224-234
Epigenomicsno. 20 (2023): 1027-1031
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