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My research is aimed at understanding the structural and cellular changes occurring at the level of the optic nerve in glaucoma using clinical and laboratory based techniques. Glaucoma is one of the most common causes of vision loss in the UK population, affecting up to 2% of the population as a whole. Classically, it is associated with increased intraocular pressure, which causes the death of retinal ganglion cells and results in a slow and, if untreated, progressive loss of vision. In most cases, peripheral vision is lost first and is usually asymptomatic. By the time a patient notices restriction of visual field, advanced damage may have occurred to the optic nerve that is usually irreversible. Treatment is aimed at the reduction of eye pressure (intraocular pressure) to prevent this vision loss. Usually, this is achieved using eye drops although, in some cases, surgery or even laser treatment may be required. One of the key problems is in identifying the disease in its earliest stages and in detecting the first signs of retinal (optic nerve) damage.
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Myungjin Kim,Jun Yong Kim,Won-Kyu Rhim,Gloria Cimaglia, Andrew Want,James E. Morgan,Pete A. Williams,Chun Gwon Park, Dong Keun Han,Seungsoo Rho
Acta Neuropathologica Communicationsno. 1 (2024): 1-16
JAMA Ophthalmologyno. 10 (2023): 956-956
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International journal of molecular sciencesno. 5 (2023): 4683-4683
Scientific Reportsno. 1 (2023): 1-7
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BRAIN COMMUNICATIONSno. 2 (2023): fcad046-fcad046
PLOS GENETICSno. 4 (2022)
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R. L. Bartlett,B. E. Frost,K. E. Mortlock, J. R. Fergusson,N. White,J. E. Morgan,R. V. North,J. Albon
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