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My research focuses on better understanding the genetic and metabolic factors in premature coronary artery disease in man. A major focus is the study of genetic factors that modulate plasma lipoproteins and apolipoprotein levels. I have undertaken four broad areas of research in the past 30 years. These include the genetics of low high-density lipoprotein (HDL) cholesterol states and biogenesis of HDL particles. In the latter area, my laboratory has studied the molecular cellular physiology of cholesterol transport. A third initiative was to set up a Cardiology/Prevention Clinic in which metabolic and genetic factors leading to coronary artery disease are studied. This clinic provides a service to patients with premature coronary artery disease. A fourth research initiative relates to the Canadian FH (Familial Hypercholesterolemia) Foundation.
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LANCETno. 10421 (2024): 55-66
Journal of Clinical Lipidology (2024)
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGYno. 2 (2024): 505-512
JOURNAL OF INTERVENTIONAL CARDIOLOGY (2024): 8646351-8646351
Kashif Khan, Bin Yu,Jean-Claude Tardif,Eric Rhéaume, Hamood Al-Kindi, Sabin Filimon,Cristina Pop,Jacques Genest,Renzo Cecere,Adel Schwertani
JACCno. 3 (2023): 100315-100315
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Canadian Journal of Health Technologiesno. 2 (2023)
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