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个人简介
Hisakazu Mihara received his Doctor of Science degree in chemistry from Kyushu University under the direction of N. Izumiya in 1986. He was a postdoctoral fellow in E. T. Kaiser’s group at the Rockefeller University, New York (1986-1988). He was appointed as an assistant professor in applied chemistry at Kyushu Institute of Technology in 1988 and was promoted to an associate professor in applied chemistry at Nagasaki University in 1993 and in bioengineering at Tokyo Institute of Technology in 1995. Currently, he is a professor in Department of Bioengineering, Graduate School of Bioscience and Biotechnology (since 2005). His research interests include peptide design and synthesis, de novo design of artificial proteins, and peptide structure-functional relationships, including self-assembling peptides for biomaterials and peptide biochips.
Selected publications:
Peptide and Protein Synthesis by Segment Synthesis-Condensation
Science, 243, 187-192 (1989)。
A Chemically Synthesized Antennapedia Homeo Domain Binds to a Specific DNA Sequence, Science, 242, 925-927 (1988)。
Engineering Peptides and Proteins that Undergo -to- Transitions
Curr. Opin. Struct. Biol., 7, 501-508 (1997)。
Design of a Peptide Undergoing Structural Transition and Amyloid Fibrillogenesis by the Introduction of Hydrophobic Defect, Chem. Eur. J., 4, 2475-2484 (1998)。
Guest-Induced Diminishment in Fluorescence Quenching and Molecule Sensing Ability of A Novel Cyclodextrin-Peptide Conjugate, J. Am. Chem. Soc., 123, 7435-7436 (2001)。
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JOURNAL OF PEPTIDE SCIENCEno. 2 (2024)
NATURE COMMUNICATIONSno. 1 (2021): 3412-3412
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