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Greg Fournier is an expert in molecular phylogenetics, inferring the evolutionary histories of genes and genomes within microbial lineages across geological timescales, specifically, the complex histories of genes involved in “horizontal gene transfer” or HGT.
His research accomplishments span many eras of Earth’s history, including the identification of the HGT origin of acetoclastic methanogenesis at a time closely linked with the Permian-Triassic mass extinction, discovering genomic clues showing oxygen-dependent sterol biosynthesis evolved in the ancestors of eukaryotes over 2 billion years ago, and inferring some of the earliest events in the evolution of life on earth from ancient gene duplication and transfer events and sequence reconstruction, including the origin of the genetic code itself. Looking forward, his research objectives include (1) the HGT-based time calibration linking events in microbial metabolism evolution to global biogeochemical changes in the oxygen, carbon, nitrogen, and sulfur cycles; (2) reconstruction of the evolutionary origins of eukaryotes; and (3) extracting the complex, ancient histories of genes having undergone recombining HGT events that obscure their true ancestries.
His research accomplishments span many eras of Earth’s history, including the identification of the HGT origin of acetoclastic methanogenesis at a time closely linked with the Permian-Triassic mass extinction, discovering genomic clues showing oxygen-dependent sterol biosynthesis evolved in the ancestors of eukaryotes over 2 billion years ago, and inferring some of the earliest events in the evolution of life on earth from ancient gene duplication and transfer events and sequence reconstruction, including the origin of the genetic code itself. Looking forward, his research objectives include (1) the HGT-based time calibration linking events in microbial metabolism evolution to global biogeochemical changes in the oxygen, carbon, nitrogen, and sulfur cycles; (2) reconstruction of the evolutionary origins of eukaryotes; and (3) extracting the complex, ancient histories of genes having undergone recombining HGT events that obscure their true ancestries.
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biorxiv(2023)
Research Square (Research Square) (2023)
Molecular biology and evolutionno. 8 (2023)
Nature Ecology & Evolutionno. 9 (2023): 1398-1407
Madeline M Paoletti,Gregory P Fournier
biorxiv(2022)
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