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Doctor Kelsoe and his collaborators have long been interested in the biology of B lymphocytes and have worked to demonstrate stochastic variable (V) gene segment use in the primary B-cell repertoire; the migrations of antigen-activated T and B lymphocytes during humoral responses; the germinal center as the primary site of V(D)J hypermutation and affinity-driven selection; the role of complement in the germinal center response and affinity maturation of serum antibodies; the nature, role, and distribution of cryptic, V(D)J recombination signals in the mammalian genome; and the basic mechanisms of central B-cell tolerance.
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论文共 327 篇作者统计合作学者相似作者
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John Barber,Chen-Hao Yeh, Helene Kirshner,Kevin Saunders,Kevin Wiehe,Ming Tian,Frederick Alt,Barton Haynes,Garnett Kelsoe
Clinical Immunology (2024): 110058
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 1 (2023): e2316964120-e2316964120
bioRxiv : the preprint server for biology (2023)
Holly C. Simmons,Akiko Watanabe, Thomas H. Oguin III, Elizabeth S. Van Itallie,Kevin J. Wiehe,Gregory D. Sempowski,Masayuki Kuraoka,Garnett Kelsoe,Kevin R. Mccarthy
PLOS BIOLOGYno. 12 (2023): e3002415-e3002415
NATURE REVIEWS IMMUNOLOGYno. 4 (2023): 265-265
bioRxiv (Cold Spring Harbor Laboratory) (2023)
NATURE REVIEWS IMMUNOLOGYno. 3 (2022): 142-158
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