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Our Lab uses genetic, metabolic engineering, metabolomics, genomics and bioinformatics tools to study the operation of amino acid metabolism in plants within the context of the entire system including transcriptional, metabolic and physiological networks. We show that besides the importance of lysine metabolism in protein synthesis, under stress conditions, lysine metabolism also cross interacts with stress-associated gene expression and also with metabolic programs associated with cellular energy. In addition, we also use metabolic engineering approach, employing bacterial genes, to study the regulation of conversion of primary metabolism into the synthesis of aromatic amino acids and the thousands of secondary metabolites derived from them in the context of the entire transcriptional and metabolic system.
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论文共 165 篇作者统计合作学者相似作者
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Simon Michaeli,Marion Clavel,Esther Lechner,Corrado Viotti,Jian Wu,Marieke Dubois,Thibaut Hacquard,Benoît Derrien, Esther Izquierdo,Maxime Lecorbeiller,Nathalie Bouteiller, Julia De Cilia,
Proceedings of the National Academy of Sciences of the United States of Americano. 45 (2019): 22872-22883
Moran Oliva, Erel Hatan,Varun Kumar,Ortal Galsurker, Ada Nisim-Levi,Rinat Ovadia,Gad Galili,Efraim Lewinsohn,Yigal Elad,Noam Alkan,Michal Oren-Shamir
Journal of experimental botanyno. 22 (2018): 5489-5506
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