基本信息
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职业迁徙
个人简介
Throughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Current work
Featuring molecular surface fingerprints to decipher protein functional properties
Bottom-up de novo design of functional proteins
Computational design of synthetic components for CAR T-cells
Computational Design of Precision Vaccines
Current work
Featuring molecular surface fingerprints to decipher protein functional properties
Bottom-up de novo design of functional proteins
Computational design of synthetic components for CAR T-cells
Computational Design of Precision Vaccines
研究兴趣
论文共 84 篇作者统计合作学者相似作者
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Casper A Goverde,Martin Pacesa, Nicolas Goldbach, Lars J Dornfeld, Petra E M Balbi,Sandrine Georgeon,Stéphane Rosset, Srajan Kapoor, Jagrity Choudhury,Justas Dauparas, Christian Schellhaas,Simon Kozlov,
bioRxiv : the preprint server for biology (2024)
Nature reviews. Molecular cell biologypp.1-15, (2024)
Ignacio Fernandez, Francois Bontems, Delphine Brun, Youna Coquin, Casper Alexander Goverde,Bruno E Correia, Antoine Gessain, Florence Buseyne, Felix A Rey,Marija Backovic
biorxiv(2024)
Anthony Marchand,Stephen Buckley,Arne Schneuing,Martin Pacesa,Pablo Gainza, Evgenia Elizarova, Rebecca Manuela Neeser, Pao-Wan Lee,Luc Reymond, Maddalena Elia,Leo Scheller,Sandrine Georgeon,
biorxiv(2024)
Cellno. 4 (2024): 999-1010.e15
Ilia Igashov, Hannes Stärk,Clément Vignac, Arne Schneuing,Victor Garcia Satorras, Pascal Frossard,Max Welling, Michael Bronstein,Bruno Correia
biorxiv(2023)
arXiv (Cornell University) (2023)
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