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Dr. Rajadhyaksha's current work is focused on examining neuronal voltage-gated L-type Ca2 channel subunits, Cav1.2 and Cav1.3 in experience-dependent plasticity. She is currently pursuing the following projects in her laboratory.1. Use of genetic mutant mouse models to delineate the roles of the voltage-gated L-type Ca2 channel subunits, Cav1.2 and Cav1.3 in psychostimulant-induced addictive behaviors and to explore the molecular mechanisms by which Cav1.2 and Cav1.3 channels mediate persistent adaptations in dopamine and glutamate neurotransmission in the rodent brain.2. Use of RNA interference (RNAi) to generate spatial and temporal knockdown of Cav1.2 and Cav1.3 to examine the molecular mechanisms of learning and memory.3. To identify mechanisms of dysregulation of Ca2 signaling in Autism spectrum disorder, a brain developmental disorder.
研究兴趣
论文共 86 篇作者统计合作学者相似作者
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Susan Lin,Aravind R Gade,Hong-Gang Wang,James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers,Jorge Nunez,Theodore H Schwartz,Anjali M Rajadhyaksha,Geoffrey S Pitt
bioRxiv : the preprint server for biology (2024)
Arlene Martínez-Rivera,Robert N Fetcho, Lizzie Birmingham, Jin X Jiu,Ruirong Yang, Careen Foord, Diego Scala-Chávez, Narmin Mekawy,Kristen Pleil,Virginia M Pickel,Conor Liston,Carlos M Castorena,
bioRxiv : the preprint server for biology (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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bioRxiv : the preprint server for biology (2023)
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Robert N. Fetcho,Baila S. Hall,David J. Estrin, Alexander P. Walsh,Peter J. Schuette,Jesse Kaminsky,Ashna Singh, Jacob Roshgodal,Charlotte C. Bavley, Viraj Nadkarni,Susan Antigua,Thu N. Huynh,
Nature Communicationsno. 1 (2023): 1-15
Jonathan E. Hackett, Viraj Nadkarni, Rabindarjeet Singh, Camille L Carthy,Susan A. Antigua,Baila S. Hall,Anjali M. Rajadhyaksha
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Jonathan Hackett, Viraj Nadkarni, Ronak S Singh, Camille L Carthy, Susan Antigua,Baila S Hall,Anjali M Rajadhyaksha
bioRxiv : the preprint server for biology (2023)
Calcium Signalspp.14-1, (2023)
Jonathan Hackett, Viraj Nadkarni, Ronak S Singh, Camille L Carthy,Susan Antigua,Baila S Hall,Anjali M Rajadhyaksha
bioRxiv : the preprint server for biology (2023)
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