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We study these processes in the nematode worm Caenorhabditis elegans, a tractable model for many aspects of skin and nervous system development and function. The C. elegans skin is a simple epithelium that encloses the entire animal during embryonic development and subsequently grows in size and complexity. The skin generates the cuticle, an apical extracellular matrix that mediates many skin functions and which serves as the animal’s exoskeleton. The nervous system contains only 302 neurons with simple stereotyped morphology. Neurons are closely associated with the epidermis, which has functions analogous to those of glial support cells.
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Seungmee Park, Nathaniel Noblett, Lauren Pitts,Antonio Colavita, Ann M Wehman,Yishi Jin,Andrew D Chisholm
bioRxiv : the preprint server for biology (2024)
Anjali Sandhu,Xiaohui Lyu, Xinghaoyun Wan, Xuefeng Meng,Ngang Heok Tang,Gilberto Gonzalez, Ishana N Syed,Lizhen Chen,Yishi Jin,Andrew D Chisholm
bioRxiv : the preprint server for biology (2024)
bioRxiv : the preprint server for biology (2024)
Susanna Birnbaum, Jozef Cohen, Alexandra Belfi,John I. Murray, Jane Adams,Andrew Chisholm,Meera V. Sundaram
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Londen C Johnson,An A Vo,John C Clancy, Krista M Myles,Murugesan Pooranachithra,Joseph Aguilera,Max T Levenson, Chloe Wohlenberg,Andreas Rechtsteiner,James Matthew Ragle,Andrew D Chisholm,Jordan D Ward
Development (Cambridge, England)no. 10 (2023)
Susanna K Birnbaum,Jennifer D Cohen,Alexandra Belfi,John I Murray, Jennifer R G Adams,Andrew D Chisholm,Meera V Sundaram
bioRxiv : the preprint server for biologyno. 9 (2023): e1010944-e1010944
Jennifer R G Adams,Murugesan Pooranachithra, Erin M Jyo, Sherry Li Zheng,Alexandr Goncharov, Jennifer R Crew,James M Kramer,Yishi Jin, Andreas M Ernst,Andrew D Chisholm
Nature communicationsno. 1 (2023): 7506-7506
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