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Over the last several decades, the genetic revolution has showed us that much of human biology, even complex behavior, is encoded in our genome. Most of the variation in genome sequence that influences neurological disease predisposition and behavioral ability occurs in the vast regulatory regions between genes. The goal of the Pfenning laboratory is to build a set of computational and experimental genomic tools to study how sequence differences in those regions influence neurons, neural circuits, disease predisposition, and behavior. By understanding the genetic mechanisms underlying neural function, we seek to uncover the cell type-specific basis of Alzheimer’s disease and addiction, as well as gain insights into how speech production ability evolved in the human lineage.
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论文共 78 篇作者统计合作学者相似作者
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Cynthia Arokiaraj, Michael Leone,Michael Kleyman,Alexander Chamessian,BaDoi N Phan, Bettega C Lopes, Vijay K Cherupally,Myung-Chul Noh, Kelly A Corrigan, Deepika Yeramosu, Michael E Franusich, Riya Podder,
biorxiv(2024)
BaDoi N. Phan,Madelyn H. Ray,Xiangning Xue, Chen Fu,Robert J. Fenster,Stephen J. Kohut,Jack Bergman,Suzanne N. Haber,Kenneth M. McCullough, Madeline K. Fish,Jill R. Glausier,Qiao Su,
Morgan E Wirthlin,Tobias A Schmid,Julie E Elie,Xiaomeng Zhang,Amanda Kowalczyk, Ruby Redlich, Varvara A Shvareva,Ashley Rakuljic, Maria B Ji, Ninad S Bhat,Irene M Kaplow,Daniel E Schäffer,
Science (New York, N.Y.)no. 6690 (2024): eabn3263-eabn3263
SCIENCEno. 6643 (2023): 364-+
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Biological Psychiatryno. 9 (2023): S247-S248
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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bioRxiv : the preprint server for biology (2023)
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Huei-Ying Chen,BaDoi N. Phan,Gina Shim,Gregory R. Hamersky,Norah Sadowski, Thomas S. O'Donnell,Srinidhi Rao Sripathy, Joseph F. Bohlen,Andreas R. Pfenning,Brady J. Maher
MOLECULAR PSYCHIATRYno. 11 (2023): 4679-4692
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