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Association Between Hemoglobin Levels and Cerebral White Matter Volume in a General Older Japanese Population: the Iki-Iki Study.

NEURORADIOLOGY(2024)

Hirosaki University | Kyoto Prefectural University of Medicine | Hirosaki University Hospital

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Abstract
Although previous studies have reported that hemoglobin levels can affect the brain, very few have focused on the association between hemoglobin levels and brain volume. We aimed to identify the influence of hemoglobin levels on brain volume measured using magnetic resonance imaging (MRI) in a large elderly population. This cross-sectional study included 2153 participants (median age, 69 years; 60.2
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Hemoglobin level,Brain volume,Magnetic resonance imaging,White Matter,Intracranial volume
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要点】:本研究探讨了血红蛋白水平与老年人脑白质体积之间的关联,发现低血红蛋白水平与脑白质体积减小有关,创新点在于对大规模老年人群进行了磁共振成像测量,以研究这一关联。

方法】:采用横断面研究设计,通过对2153名老年人(中位年龄69岁)进行MRI脑部扫描,分析血红蛋白水平与脑白质体积之间的关系。

实验】:实验在一般老年日本人群中开展,使用了MRI技术进行脑部扫描,数据集名称未在摘要中提及,但结果显示低血红蛋白水平与脑白质体积减小有显著相关性。