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Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression

Renqi Xu, Haibin Zhou,Longchuan Bai,Donna McEachern,Dimin Wu,Ranjan Kumar Acharyya,Mi Wang,Jelena Tosovic,Chao-Yie Yang,Krishnapriya Chinnaswamy,Jennifer L. Meagher,Jeanne A. Stuckey, Cai Liu,Meilin Wang,Bo Wen,Duxin Sun,Shaomeng Wang

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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