Cell-autonomous IL6ST Activation Suppresses Prostate Cancer Development Via STAT3/ARF/p53-driven Senescence and Confers an Immune-Active Tumor Microenvironment Christina Sternberg , Martin Raigel , Tanja Limberger , Karolína Trachtová , Michaela Schlederer , Desiree Lindner , Petra Kodajova , Jiaye Yang , Roman Ziegler , Jessica Kalla , Stefan Stoiber , Saptaswa Dey , Daniela Zwolanek , Heidi A. Neubauer , Monika Oberhuber , Torben Redmer , Václav Hejret , Boris Tichy , Martina Tomberger , Nora S. Harbusch , Jan Pencik , Simone Tangermann , Vojtech Bystry , , Gerda Egger , Sarka Pospisilova , Robert Eferl , Peter Wolf , Felix Sternberg , Sandra Högler , Sabine Lagger , Stefan Rose-John , Lukas Kenner Molecular Cancer（2024）
关键词
Prostate cancer, IL6ST/STAT3 signaling, L-gp130, Senescence, Senescence-associated secretory phenotype, Tumor microenvironment, Immune cell infiltration, Cytotoxic T-cells
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