Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Female Patients and the Elderly: an Update Analysis from the Global Burden of Disease Study 2021.

Pojsakorn Danpanichkul,Kwanjit Duangsonk,Agnes H Y Ho,Passisd Laoveeravat, Chawinthorn Vuthithammee,Disatorn Dejvajara,Vitchapong Prasitsumrit, Thanida Auttapracha,Busara Songtanin,Panu Wetwittayakhlang,Rashid N Lui, Gursimran Singh Kochhar, Siew C Ng,Francis A Farraye,Karn Wijarnpreecha

The American journal of gastroenterology（2024）

Department of Internal Medicine | Department of Microbiology | Department of Pathology | Faculty of Medicine | Division of Gastroenterology and Hepatology

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Abstract

INTRODUCTION:To update the global burden of inflammatory bowel disease (IBD) using data from the Global Burden of Disease 2021. METHODS:Data from Global Burden of Disease 2021 were analyzed to assess the IBD burden. RESULTS:In 2021, there were 375,140 new cases and 3.83 million total cases of IBD. Elderly onset IBD accounted for 11% of incidences. 167 countries increased IBD incidence rate, with rates rising in female patients (APC: +0.06%) and the elderly (APC: +0.14%) but stable in male patients and the overall population. DISCUSSION:Although the global burden of IBD has decreased overall, it has increased in female patients and the elderly.

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【要点】：该研究通过全球疾病负担研究2021数据更新，发现炎症性肠病（IBD）在女性患者和老年人群中的发病率不成比例地增加。

【方法】：研究采用全球疾病负担2021的数据进行分析，以评估IBD的疾病负担。

【实验】：研究分析了2021年的IBD新发病例数为375,140例，总病例数为3.83百万例，其中老年发病的IBD占11%，在167个国家中IBD发病率上升，女性患者的发病率年增长率为+0.06%，老年人的年增长率为+0.14%，而在男性患者和总体人群中保持稳定。