Glove Phenomenon Detected by Total-Body PET/CT with 68GA-DOTATATE

Abstract Accidental intra-arterial injections of radiotracers are rare events resulting in a specific imaging pattern, described as “hot-forearm,” “hot-hand,” “glove-phenomenon,” or “glove-like pattern.” We present a case 68Ga-DOTATATE total-body PET/CT for restaging of a neuroendocrine tumor, where intra-arterial misinjection resulted in a glove phenomenon. Since patients may present with minimal symptoms, like in this case, and PET findings may only be seen at the distal upper extremity (placed above the head), these accidental injections may be more frequently detected with total-body PET/CT due to the longer field-of-view. Radiologists and technologists should be aware of this possibility to avoid accidental misinjections.