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Bulk Integrated Single-Cell-spatial Transcriptomics Reveals the Impact of Preoperative Chemotherapy on Cancer-Associated Fibroblasts and Tumor Cells in Colorectal Cancer, and Construction of Related Predictive Models Using Machine Learning

Shangshang Hu,Jian Qin, Muzi Ding, Rui Gao, QianNi Xiao, Jinwei Lou, Yuhan Chen,Shukui Wang,Yuqin Pan

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE(2025)

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关键词
Colorectal cancer (CRC),Preoperative chemotherapy (PC),Cancer associated fibroblasts (CAFs),Machine learning
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