Supplementary Figure S4 from Early Detection of Malignant and Premalignant Peripheral Nerve Tumors Using Cell-Free DNA Fragmentomics

R. Taylor Sundby, Jeffrey J. Szymanski, Alexander C. Pan,Paul A. Jones, Sana Z. Mahmood, Olivia H. Reid, Divya Srihari,Amy E. Armstrong, Stacey Chamberlain, Sanita Burgic, Kara Weekley, Béga Murray, Sneh Patel,Faridi Qaium, Andrea N. Lucas, Margaret Fagan,Anne Dufek, Christian F. Meyer,Natalie B. Collins, Christine A. Pratilas,Eva Dombi,Andrea M. Gross,AeRang Kim,John S.A. Chrisinger,Carina A. Dehner,Brigitte C. Widemann,Angela C. Hirbe, Aadel A. Chaudhuri,Jack F. Shern

crossref（2024）

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Abstract

Supplemental Figure 4. 4-mer end motifs across F-profiles. Comprehensive view of the distribution and prevalence of each possible 4-mer end motif within each of the six distinct F-profiles derived from non-negative matrix factorization (NMF) (Methods). The analysis highlights distinct end motif compositions and non-random distribution of end nucleotides across the F-profiles.

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