Therapeutic Single-Cell Landscape: Methotrexate Exacerbates Interstitial Lung Disease by Compromising the Stemness of Alveolar Epithelial Cells under Systemic Inflammation

Sung Hae Chang,Seyoung Jung, Jeong Jun Chae,Jeong Yeon Kim,Seon Uk Kim,Ji Yong Choi, Hye-Jeong Han,Hyun Taek Kim, Hak-Jae Kim,Hyun Je Kim,Woong Yang Park, Jeffrey A. Sparks,Eun Young Lee, Jeong Seok Lee

EBIOMEDICINE（2024）

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Key words

Rheumatoid arthritis-associated interstitial lung disease,Methotrexate,Tumor necrosis factor inhibitor,SKG mouse,Macrophage differentiation,Th17 cell activation,Fibrosis

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