Dynamic Allostery Drives Autocrine and Paracrine TGF-β Signaling

Mingliang Jin,Robert I. Seed, Guoqing Cai, Tiffany Shing, Li Wang, Saburo Ito,Anthony Cormier,Stephanie A. Wankowicz,Jillian M. Jespersen,Jody L. Baron,Nicholas D. Carey,Melody G. Campbell,Zanlin Yu,Phu K. Tang,Pilar Cossio, Weihua Wen,Jianlong Lou,James Marks,Stephen L. Nishimura,Yifan Cheng

Cell（2024）

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关键词

TGF-b1,TGF-b3,latency,activation,furin,TGF-b signaling,avb8 integrin,dynamic allostery,regulatory T cells,single-particle cryo-EM,autocrine signaling,paracrine signaling,entropy redistribution

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