Study of Peliosanthes Micrantha Medicinal Plant: UHPLC‐Q‐TOF‐MS Analysis of Phytochemicals and Antioxidant Activity

Purpose: The medicinal herb Peliosanthes micrantha Aver. & N. Tanaka has been used in traditional Vietnamese medicine to treat various diseases such as diuretic, hemorrhoids, jaundice, asthma, diarrhea, blennorrhagia and for its fatigue, detoxification and male wellness effects. Till now, we have not found any research of this herbal plant. This study explores the first chemical information and antioxidant activity of the species. Methodology: Three procedures were applied to extract P. micrantha rhizomes: 1) extraction by ethanol, 2) then sequentially by water, and 3) extraction by water. UHPLC-Q-TOF spectroscopy was used to study three extracts. Antioxidant activity was measured by DPPH assay. Findings: In alcoholic extract, UHPLC-Q-TOF-MS tentatively identified three known compounds undescribed in the Peliosanthes species, namely pumilaside A, pumilaside C, and β–sitosterol together with one known compound of glycoside J-3, previously isolated in the Peliosanthes sinica. Not any identified compounds was found in water extracts. All three extracts of P. micrantha rhizomes showed mild DPPH antioxidant activity. Unique contribution to theory, practice and policy: The experimental findings contribute to the chemical literature of Vietnamese natural flora. Peliosanthes micrantha should be further studied for pharmaceutical activities.