Association Between Serum Osmolality and Deteriorating Renal Function in Patients with Acute Myocardial Infarction: Analysis of the MIMIC- IV Database
BMC cardiovascular disorders(2024)
摘要
To investigate the association between serum osmolality and deteriorating renal function in patients with acute myocardial infarction (AMI). Three thousand eight hundred eighty-five AMI patients from the Medical Information Mart for Intensive Care IV were enrolled for this study. The primary outcome was deteriorating renal function. Secondary outcomes included the new-onset of acute kidney injury (AKI) and progress of AKI. < 293.2725 mmol/L was defined as low serum osmolality, and ≥ 293.2725 mmol/L as high serum osmolality based on upper quartile. Univariate and multivariate logistic regression models were used to explore the associations between serum osmolality and the development of deteriorating renal function, the new-onset of AKI and progress of AKI among AMI patients. Subgroup analysis was also conducted. One thousand three hundred ninety-three AMI patients developed deteriorating renal function. After adjusting all confounding factors, high serum osmolality was associated with increased risk of deteriorating renal function [odds ratio (OR) = 1.47, 95
更多查看译文
关键词
Acute myocardial infarction,Serum osmolality,Deteriorating renal function,Acute kidney injury,Association
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要