Amiodarone Induced Interstitial Lung Disease: an Enigma

Prakash Aryal, Srijan Pantha, Kum Bahadur Gurung, Augraj Uprety, Nensi Shah, Anup Timsina, Dipesh Mandal, Krishna Chandra Yadav, Aarati Adhikari,Rejina Shahi,Deebya Raj Mishra,Narendra Bhatta

Nepalese Respiratory Journal(2024)

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Abstract
Amiodarone is an anti-arrhythmic drug that has potential to cause Interstitial Lung Disease (ILD) commonly non-specific Interistitial pneumonia. We present a 75-year male presenting with gradual onset progressive shortness of breath and dry cough after undergoing coronary artery bypass grafting (CABG) and was kept on amiodarone therapy post-surgery to control arrhythmias. The patient was diagnosed as amiodarone induced Non-Specific Interstitial Pneumonia (NSIP) after excluding alternative diagnosis. Early recognition and stoppage of amiodarone, prompt treatment with corticosteroid and respiratory support had favorable clinical outcome in this case.
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