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Joint Single-Cell Genetic and Transcriptomic Analysis Reveal Pre-Malignant SCP-like Subclones in Human Neuroblastoma

Thale K. Olsen,Jörg Otte,Shenglin Mei,Bethel Tesfai Embaie,Polina Kameneva,Huaitao Cheng,Teng Gao,Vasilios Zachariadis,Ioanna Tsea,Åsa Björklund,Emil Kryukov, Ziyi Hou, Anna Johansson,Erik Sundström,Tommy Martinsson,Susanne Fransson,Jakob Stenman,Shahrzad Shirazi Fard,John Inge Johnsen,Per Kogner,Igor Adameyko,Martin Enge,Peter V. Kharchenko,Ninib Baryawno

Molecular Cancer（2024）

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关键词
Neuroblastoma,Schwann cell precursors,Childhood cancer,Tumor heterogeneity,Tumor evolution,Clonality,Development,Single-cell sequencing,Multi-omics
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