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Effect of Opaganib on Supplemental Oxygen and Mortality in Patients with Severe SARS-CoV-2 Based Upon FIO2 Requirements

Fernando Carvalho Neuenschwander,Ofra Barnett-Griness,Stefania Piconi,Yasmin Maor,Eduardo Sprinz,Nimer Assy, Oleg Khmelnitskiy, Nikita V Lomakin, Boris Mikhailovich Goloshchekin, Ewelina Nahorecka, Adilson Joaquim Westheimer Calvacante, Anastasia Ivanova,Sergey Vladimirovich Zhuravel, Galina Yurevna Trufanova,Stefano Bonora,Amer Saffoury,Ami Mayo,Yury G Shvarts,Giuliano Rizzardini, Rogerio Sobroza de Mello, Janaina Pilau, Alexey Klinov,Benjamin Valente-Acosta, Oleg Olegovich Burlaka, Natalia Bakhtina,Maskit Bar-Meir,Ivan Nikolaevich Shishimorov,Jose Oñate-Gutierrez, Cristian Iván García Rincón, Tatiana Ivanovna Martynenko, Ludhmila Abrahão Hajjar, Ana Carolina Nazare de Mendonca Procopio, Krzysztof Simon, Walter Gabriel Chaves Santiago, Adam Fronczak,Conrado Roberto Hoffmann Filho, Osama Hussein,Vladimir Aleksandrovich Martynov,Guido Chichino, Piotr Blewaska, Jacek Wroblewski, Sergio Saul Irizar Santana, Andres Felipe Ocampo Agudelo,Adam Barczyk, Rachael Lask Gerlach, Eppie Campbell,Aida Bibliowicz,Reza Fathi,Patricia Anderson,Gilead Raday, Michal Klein,Clara Fehrmann,Gina Eagle,Vered Katz Ben-Yair,Mark L Levitt

Microorganisms(2024)

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关键词
opaganib,COVID-19,sphingosine kinase 2,ABC294640,SARS-CoV-2 pneumonia,trial registration number: NCT04467840
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