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Residency in Long-Term Care Facilities: an Important Risk Factor for Respiratory Syncytial Virus Hospitalization.

JOURNAL OF INFECTIOUS DISEASES(2024)

Univ Rochester | Beacon Epidemiol Associates

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Abstract
Older age and comorbid conditions increase risk for severe for respiratory syncytial virus (RSV). Skilled nursing facilities (SNFs) and assisted living (AL) facilities represent an intersection of risk factors. In a 3-year prospective study in Rochester, New York, we compared the population-based incidence of RSV-associated hospitalization for community-dwelling (CD), SNF, and AL adults aged >= 65 years. Their median ages were 76, 83 and 86 years, respectively, and dementia and congestive heart failure (CHF) were more prevalent among SNF and AL residents. The average annual incidences were 117 (95% confidence interval, 104-132), 440 (307-629) and 740 per 100 000 persons (523-1045), respectively, for CD, SNF, and AL adults aged >= 65 years, demonstrating a need for unequivocal RSV vaccine recommendations in SNF and AL residents. In a 3-year prospective, population-based incidence study, respiratory syncytial virus hospitalization rates among adults aged >= 65 years were 3-9 and 3-4 times higher for those admitted from assisted living or skilled nursing facilities, respectively, compared with community-dwelling adults.
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RSV hospitalization,RSV vaccine,long-term care facilities,RSV population-based incidence,Skilled Nursing Facilities
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要点】:该研究发现长期护理设施居住是老年人患呼吸道合胞病毒(RSV)住院的重要风险因素,指出有必要为长期护理设施居民提供明确的RSV疫苗接种建议。

方法】:通过在纽约罗切斯特进行为期3年的前瞻性研究,比较了社区居住、熟练护理设施(SNF)和辅助生活(AL)的65岁及以上成人的RSV相关住院率。

实验】:研究采用前瞻性队列研究设计,收集了来自社区居住、SNF和AL的65岁及以上成人的数据,数据集名称未在文中提及,结果显示SNF和AL居民的RSV住院率比社区居住的老年人高出3-9倍和3-4倍。