Chédiak-Higashi Syndrome

Nils Peters,Martin Dichgans, S. Surendran, J. M. Argiles, F. López‐Soriano, S. Busquets,Klaus Dittmann, H. Rodemann, A. Sindrilaru,Cord Sunderkötter,Hiroshi Watanabe, D. Roden, G. Feuerstein,Robert R. Ruffolo, R. Knöll, S. Sen‐Chowdhry,Deirdre Ward, W. McKenna, J. Mogensen, M. Nadkarni, F. E. Martin, Nicholas A. Jacques,Neil Hunter,Markus Böhm, T. Luger, Tilman Grune,Nicola Longo, C. A. D. S. Filippo, E. Schwarz, M. Pasquali, Elardus Erasmus, L. J. Mienie, M. Deschauer,Stephan Zierz, D. T. Loots,Lee A. Denson,Helen C. Su,Michael J. Lenardo, H. McDermid, G. Eisenhofer, O. D. L. Calle-Martín,N. Casamitjana, C. Woellner, B. Grimbacher,Detlef Schuppan, W. Lisch,Berthold Seitz,Andreas R. Janecke,Tommie V. McCarthy,Carina Wallgren-Pettersson, J. Haan, Michael T. Wunderlich, N. Revencu, M. Vikkula,Akira Honda, S. Lalani,John W. Belmont, J. I. Borissoff, H. Cate, Takatoshi Kasai,Daniel Markovich, M. Trauner,Carlo Selmi, M. Gershwin, M. Lyons, Kirk J. Maurer,Martin C. Carey, F. Lammert, T. Sauerbruch,Peter L. M. Jansen, Holger Sudhoff, S. Dahl, Detlev Ameis,Muhammad Faiyaz-Ul-Haque, Syed Hassan Ejaz Zaidi, Caroline Silve, Piero Pavone, Rosario R. Trifiletti, Friedrich Asmus, P. Weckerle, G. Schwanitz, Barbara Busert, T. Thiagarajah, Walter Muir, B. Pickard, A. Cleare, H. Scharnagl, Winfried März,Ralf Kubitz, D. Häussinger, Norbert Schwenzer,Alexander K. C. Leung, W. Robson,Andrew L. Wong, Y. Güzelcan, F. Trotta, A. L. Monaco, R. Sauve, Todd D. Rozen,Gloria L. David, D. Zeldin, P. S. Rao,Anne M. Molloy, J. Scott, G. Somay, S. Meo,Joshua Fierer, M. Berneburg,Thomas Schwarz, J. Schölmerich,Anne Katrin Lampe, Kate Bushby, William J. Speake, J. Simpson, H. Uronis, G. Blobe,Diego Franco, A. Aránega,Eggert Stockfleth, I. Nindl, C. Hamel, F. Riepe, Erich C. Strauss, V. Oji, H. Traupe,Thomas J. Frieling,Andrea Cavani, G. Girolomoni,Randolf Brehler, O. Steinlein, J. Uriu-Adams, J. Deybach, H. Puy, Michael L. S. Ma, Patrick T. S. Ma, J. Wierzba, A. Selicorni, Y. V. Kodolitsch, Wulf Ito, N. Maulik, R. Voisard,Hiroki Teragawa, K. Chayama,Renzo Guerrini, Carla Marini, E. Parrini,Alexander Storch,Johannes Schwarz,Sonja Ständer, Kam-Iun Ellis Hon, C. Chu, Olaf A. Bodamer, S. Stöckler‐Ipsiroglu,Tatsuro Kondoh, O. Shimokawa,Naoki Harada,Hiroyuki Moriuchi, K. Schulmann, C. Pox, W. Schmiegel,James E. Crowe, Nan Hatch, M. Bothwell, H. Willenberg,Stefan R. Bornstein, Z. Urban, F. Borgia, F. Guarneri, M. Vaccaro, D. Metze,Karl Kunzelmann, Marcus M Mall, Paul Cheung-Lung Choi,William A. Gahl, Thomas Knoll,Albrecht Hesse, M. Jaksch

semanticscholar（2020）

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摘要

Chediak-Higashi syndrome is a condition that affects many parts of the body, particularly the immune system. This disease damages immune system cells, leaving them less able to fight off invaders such as viruses and bacteria. As a result, most people with Chediak-Higashi syndrome have repeated and persistent infections starting in infancy or early childhood. These infections tend to be very serious or life-threatening.

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