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Predictors of Favorable Functional Outcomes for Elderly Patients Undergoing Endovascular Thrombectomy for Acute Ischemic Stroke

Qingjia Liang,Mingzhu Feng,Milagros Galecio-Castillo, Amine Awad, Jincheng Chen, Lanzhu Luo,Wenjun Liang, Jicai Ma,Sijie Zhou, Adam A. Dmytriw, Fernando Pico, Yuzheng Lai, Lingjuan Liu,Yimin Chen, Yu Sun,Shuiquan Yang

European Journal of Medical Research(2024)

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摘要
The aim of this study was to identify factors that predict favorable functional outcomes in elderly patients with large-vessel occlusion acute ischemic stroke (LVO-AIS) who underwent mechanical thrombectomy (MT). We conducted a retrospective observational study using the prospectively maintained Bigdata Observatory for Stroke of China (BOSC) to identify eligible patients who underwent MT for LVO-AIS at four comprehensive stroke centers between August 2019 and February 2022. Inclusion criteria included patients aged 80 years or older with a baseline modified Rankin Scale (mRS) 0–2, baseline National Institutes of Health Stroke Scale (NIHSS) > 6, baseline Alberta Stroke Program Early CT Score (ASPECTS) > 6 who received treatment within 24 h from symptom onset. Pertinent demographic, clinical, and procedural variables were collected. Multivariable regression analyses were performed to identify predictors of favorable long-term functional outcomes, defined as mRS 0–2 at 90 days. A total of 63 patients were included in the study with a mean age of 83 years. Patients with previous diagnosis of atrial fibrillation were more likely to have a favorable functional outcome (OR 2.09, 95
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关键词
Ischemic stroke,Thrombectomy,Elderly,Atrial fibrillation,Outcomes
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