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CSU-ALS Certified Centers Are Associated with Improved Failure to Rescue after Cardiac Arrest: A Propensity Score Match Analysis

Matthew P. Weber,Raymond J. Strobel,Anthony V. Norman, Abhinav Kareddy,Andrew Young, Steven Young, Mohamad El Moheb,Sean W.W. Noona,Alexander M. Wisniewski,Mohammed Quader,Michael Mazzeffi,Leora T. Yarboro, Nicholas R. Teman

The Journal of Thoracic and Cardiovascular Surgery(2024)

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Abstract
Objective The impact of Cardiac Surgical Unit - Advanced Life Support (CSU-ALS) training on failure to rescue after cardiac arrest (FTR-CA) is unknown. We hypothesized that institutional CSU-ALS certification would be associated with lower FTR-CA. Methods Patients undergoing Society of Thoracic Surgeons (STS) index operations from 2020-2023 from a regional collaborative were analyzed. Each institution was surveyed regarding its status as a CSU-ALS certified center. Patients stratified by CSU-ALS certification were 1:1 propensity score matched with subsequent multivariable model reviewing associations with failure to rescue after cardiac arrest. Results A total of 12209 patients were included in the study period across 15 institutions. Eight centers reported CSU-ALS certification. After propensity score matching, two patient cohorts were formed (n = 3557). Patients at CSU-ALS centers had higher rates of ICU readmission (3.9% vs 2.3%, p<0.01) and total OR time (340 min vs 323 min, p<0.01). Hospital readmission was less likely in the CSU-ALS centers (9.0% vs 10.1%, p <0.01). There was no difference in the rate of post-operative cardiac arrest (1.8% vs 2.2 %, p = 0.24) or operative mortality (2.5% vs 2.9%, p = 0.30). After risk-adjustment, CSU-ALS centers (OR 0.30 [CI 0.12 – 0.72], p <0.01) and higher-volume centers (OR 0.15 [CI 0.03 – 0.74], p = 0.02) had reduced odds of FTR after cardiac arrest. Conclusions Centers with CSU-ALS certification are associated with a lower risk-adjusted likelihood of FTR after cardiac arrest. This highlights the importance of well-trained staff and treatment algorithms in the care of post-operative cardiac surgery patients.
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Key words
Cardiac Surgical Unit,Advanced Life Support,Cardiac Arrest,Perioperative Care
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