[Noninvasive Rejection Surveillance after Solid Organ Transplantations: Analysis of the Donor-Derived Cell-Free DNA].

Solid organ transplant rejection is a major etiological factor of graft dysfunction, hospitalisation, and death. Invasive biopsy is still considered the gold standard method of monitoring rejection; however, besides the need for hospitalisation, common concerns are its complications and the high interobserver variability. Thus, noninvasive methods for graft injury, and it can be isolated from the recipient's sera. Elevated dd-cfDNA levels precede the diagnosis of rejection on biopsy and possess high negative predictive value. We aimed to analyze the role of dd-cfDNA testing after