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A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes

ANTIBODIES(2024)

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关键词
monoclonal antibodies,subcutaneous dosing,physiologically based pharmacokinetic modeling,antigen-presenting cells,neonatal Fc receptor (FcRn)
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