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Alzheimer’s Disease Risk Gene CD2AP is a Dose-Sensitive Determinant of Synaptic Structure and Plasticity

Matea Paveskovic,Ruth B. De-Paula,Shamsideen A. Ojelade,Evelyne K. Tantry,Mikhail Y. Kochukov, Suyang Bao,Surabi Veeraragavan, Alexandra R. Garza,Snigdha Srivastava, Si-Yuan Song,Masashi Fujita,Duc M. Duong,David A. Bennett,Philip L. De Jager,Nicholas T. Seyfried,Mary E. Dickinson,Jason D. Heaney,Benjamin R. Arenkiel,Joshua M. Shulman

Human Molecular Genetics（2024）

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Key words
Alzheimer's disease,synapse,CD2AP,proteomics,proteostasis,plasticity,haploinsufficiency,endocytosis,apolipoproteins,lipid metabolism
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