Joint Use of Population Pharmacokinetics and Machine Learning for Prediction of Valproic Acid Plasma Concentration in Elderly Epileptic Patients

Pan Ma,Shenglan Shang,Yifan Huang, Ruixiang Liu,Hongfan Yu, Fan Zhou, Mengchen Yu, Qin Xiao, Ying Zhang, Qianxue Ding,Yuxian Nie, Zhibiao Wang,Yongchuan Chen,Airong Yu,Qiuling Shi

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES（2024）

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关键词

Valproic acid,Elderly epileptic patients,Machine learning,Population pharmacokinetics,Feature selection,Precision medicine

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