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Sensing of Liver-Derived Nicotinamide by Intestinal Group 2 Innate Lymphoid Cells Links Liver Cirrhosis and Ulcerative Colitis Susceptibility

Jing Shen, Zhen Li,Xiaoyu Liu,Mengqi Zheng, Peng Zhang, Yatai Chen, Qiuheng Tian,Wenyu Tian,Guanjun Kou,Yanyan Cui,Bowen Xu,Yunjiao Zhai,Weijia Li,Xiaohuan Guo,Ju Qiu,Chunyang Li,Ran He,Lixiang Li,Chunhong Ma,Yanqing Li,Xiuli Zuo,Detian Yuan,Shiyang Li

Advanced science (Weinheim, Baden-Wurttemberg, Germany)（2024）

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Key words
group 2 innate lymphoid cells,liver injury,liver-gut axis,NAD(+) metabolism,nicotinamide phosphoribosyltransferase,ulcerative colitis
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