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Celastrol Induces DNA Damage and Cell Death in BCR-ABL T315I-mutant CML by Targeting YY1 and HMCES

Fan Yang,Hongchao Zhou,Piao Luo,Lin Jia,Mengyun Hou,Jingnan Huang, Lin Gao,Qian Zhang,Yudong Guan, Honglei Bao,Baotong Zhang,Liping Liu,Chang Zou,Qinhe Yang,Jigang Wang,Lingyun Dai

Phytomedicine（2024）

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Key words
Chronic myeloid leukemia,Drug resistance,Celastrol,DNA damage,YY1,HMCES
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