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A First-in-Class Pyrazole-isoxazole Enhanced Antifungal Activity of Voriconazole: Synergy Studies in an Azole-Resistant Candida Albicans Strain, Computational Investigation and in Vivo Validation in a Galleria Mellonella Fungal Infection Model.

Sveva Pelliccia,Pasquale Russomanno,Simona Barone, Baptiste Mateu,Antonella Ilenia Alfano, Martina Miranda,Lorena Coretti,Francesca Lembo,Marialuisa Piccolo,Carlo Irace,Laura Friggeri,Tatiana Y. Hargrove,Aaron Curtis,Galina I. Lepesheva,Kevin Kavanagh,Elisabetta Buommino,Margherita Brindisi

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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