Development of a Functional Beige Fat Cell Line Uncovers Independent Subclasses of Cells Expressing UCP1 and the Futile Creatine Cycle

Ariana Vargas-Castillo,Yizhi Sun, Amanda L. Smythers, Louisa Grauvogel,Phillip A. Dumesic,Margo P. Emont,Linus T. Tsai,Evan D. Rosen, Nathan W. Zammit,Sydney M. Shaffer,Martha Ordonez,Edward T. Chouchani,Steven P. Gygi,Tongtong Wang, Anand K. Sharma,Miroslav Balaz,Christian Wolfrum,Bruce M. Spiegelman

Cell metabolism（2024）

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functional beige cell line,thermogenesis,aP2-Prdm16 transgenic mice,futile creatine cycle,UCP1,TNAP,Alpl gene,immortalized beige adipocytes,SV40 large T antigen

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