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Single-cell Atlas Profiling Revealed Cellular Characteristics and Dynamic Changes after PD-1 Blockade Therapy of Brain Metastases from Laryngeal Squamous Cell Carcinoma

Yunzhi Zou,Hao Duan, Zekun Deng, Rong Xiang, Jixiang Zhao,Zhenhua Zhang,Wanming Hu,Yuanzhong Yang, Zeming Yan, Shujuan Wen,Zexian Liu,Gao Zhang,Yonggao Mou,Depei Li,Xiaobing Jiang

Molecular and Cellular Biochemistry(2024)

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关键词
Laryngeal squamous cell carcinoma,PD-1 blockade,Brain metastasis,Single‐cell RNA sequencing,Immunosuppressive microenvironment,Tumor heterogeneity
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