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Molecular Design and Evaluation of Aza-Polycyclic Carbamoyl Pyridones As HIV-1 Integrase Strand Transfer Inhibitors

Toshiyuki Akiyama,Brian A. Johns,Yoshiyuki Taoda,Hiroshi Yoshida,Teruhiko Taishi,Takashi Kawasuji,Hitoshi Murai,Tomokazu Yoshinaga, Akihiko Sato,Takahiro Seki, Mikiko Koyama,Shigeru Miki,Shinobu Kawauchi-Miki, Akemi Kagitani-Suyama,Tamio Fujiwara

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2024）

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关键词
HIV integrase,INSTIs (integrase strand transfer inhibitors),Long-acting,Scaffold hopping
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