Stromal Senescence following Treatment with the CDK4/6 Inhibitor Palbociclib Alters the Lung Metastatic Niche and Increases Metastasis of Drug-Resistant Mammary Cancer Cells

Gregory T. Gallanis,Ghada M. Sharif,Marcel O. Schmidt, Benjamin N. Friedland, Rohith Battina,Raneen Rahhal, John E. Davis, Jr.,Irfan S. Khan,Anton Wellstein,Anna T. Riegel

Cancers（2023）

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CDK4/6 inhibitors,palbociclib,abemaciclib,lung metastasis,mammary cancer,senescence,endothelium,p16-INK-ATTAC,senolytic,macrophage,monocyte,p16,p21,TGF-β

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