RIPK1: Inflamed if You Do, Inflamed if You Don’t

Immunity（2024）

Department of Human Genetics | Department of Immunology

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Abstract

RIPK1 is known as a driver of cell death and inflammation. In this issue of Immunity, Imai et al. and Mannion et al. find that these same processes are also induced by RIPK1 inactivation and highlight the therapeutic potential of RIPK1 elimination.

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Pretraining has recently greatly promoted the development of natural language processing (NLP)
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【要点】：本研究发现RIPK1不仅在激活时能驱动细胞死亡和炎症，其在失活状态下也能引发相同过程，并提出RIPK1消除的潜在治疗价值。

【方法】：Imai等人及Mannion等人通过研究RIPK1的功能，探讨了其在细胞死亡和炎症中的作用机制。

【实验】：具体实验细节未在摘要中提供，但研究揭示了RIPK1失活在细胞死亡和炎症中的影响。数据集名称未提及。