A Renaissance of Cerebral Cavernous Malformation Proteins in Vascular Physiology

Nature cardiovascular research（2024）

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摘要

The discovery of the genes causing cerebral cavernous malformation (CCM) initially heralded a fruitful search for etiopathogenic molecular pathways in this rare cerebrovascular disease. Recent studies have identified the relevance of CCM proteins for much more common vascular biology and pathologies.

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