Hepatic Glucokinase Regulatory Protein and Carbohydrate Response Element Binding Protein Attenuation Reduce De Novo Lipogenesis but Do Not Mitigate Intrahepatic Triglyceride Accumulation in ALDOB Deficiency

Amee M. Buziau,Maaike H. Oosterveer,Kristiaan Wouters,Trijnie Bos,Dean R. Tolan,Loranne Agius,Brian E. Ford,David Cassiman,Coen D. A. Stehouwer,Casper G. Schalkwijk,Martijn C. G. J. Brouwers

MOLECULAR METABOLISM（2024）

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关键词

Fructose,Aldolase B,GKRP,ChREBP,de novo lipogenesis,Glucose signalling

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