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The Value of 68Ga-Psma PET/CT in the Diagnosis of Intracapsular Prostate Cancer with a Poor Prognosis.

Yajing Wang, Jieping Song,Lulu Yang,Wencheng Li,Wei Wang, Aiqing Ji, Liwei Wang,Feng Wang

Discover Oncology(2024)

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摘要
To evaluate the diagnostic value of 68Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) for intracapsular prostate cancer with a poor prognosis (PPC) and no extracapsular invasion or distant metastasis. The PET/CT images and clinical data of 221 patients were retrospectively analyzed. These patients all had clear pathological results. The maximum standard uptake value (SUVmax) of the main lesions was measured at the postprocessing workstation and was tested for correlation with the pathological score. The diagnostic accuracy was calculated using the receiver operating characteristic (ROC) curve, and the best diagnostic threshold was calculated. The correlation between SUVmax and the International Society of Urological Pathology Grade Group (GG) was also analyzed. The pathological results of the 221 patients were 48 benign lesions and 173 malignant lesions, including 81 PPC. Low-, intermediate-, and high-risk prostate cancers made up 21.97
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关键词
Prostate,Tumor,Positron-emission tomography,Prostate-specific membrane antigen
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