Discovery of Novel Indazole Derivatives As Second-Generation TRK Inhibitors

Qiaohua Qin, Shuyu Lu,Zhiqiang Guo, Zhuo Li,Qinglin Fu,Xin Wang,Tianxiao Wu,Yixiang Sun,Nian Liu,Haoyu Zhang,Dongmei Zhao,Maosheng Cheng

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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TRK inhibitors,Indazole,NTRK gene fusion,Drug resistance,Anticancer

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